In Chinese, the KFC slogan "finger lickin' good" comes out as "eat your fingers off".
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Glucose (sugar) has an opposite “handed” isomer L-glucose that tastes identical and isn't metabolized as sugar, so it's safe for diabetics. Unfortunately, L-glucose costs 50% more than gold.
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Coffee comes from an edible fruit. The coffee cherry is sweet and tastes like watermelon, rosewater, and hibiscus all at once.
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Vanilla flavoring is sometimes made with an ingredient from beaver pee.
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